Substance Identity
CAS Number 124-07-2
Chemical Name Octanoic acid
Type of substance Organic
SMILES O=C(O)CCCCCCC
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P QSAR
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT QSAR
DSL Quantity range (tonnes/year) >1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Robust Study Summary (biodegradation result)
124072.doc
Predicted Ultimate degradation half-life (days) 8.67
MITI probability of biodegradation 0.8903
TOPKAT probability of biodegradation 1
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 1.281

Underlying data regarding Bioaccumulation

Empirical Log Kow 3.05
Log Kow predicted by KowWin 3.03
Log BAF T2MTL predicted by Gobas 1.86508022126055
Log BCF 5% T2LTL predicted by Gobas 1.7643607607128
Log BCF Max predicted by OASIS 2.42711746646358
Log BCF predicted by BCFWIN 0.5

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 209.1
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 209.1
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 115.03
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 24.5644
Toxicity to fish (LC50 in mg/l) as predicted by Aster 13.598557
Toxicity to fish (LC50 in mg/l) as predicted by PNN 172.23225
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 0.0056
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 15.904
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 10.652
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 1.15E-001

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Greatest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment

Carcinogencity

Screening Outcome Negative
Screening Method
Data Results
Reference TOPKAT v6.2 CASETOX v1.56 Harkin, 1968, J AM OIl Chem Soc, 45:26 (as cited in BIBRA, 1988)

Genotoxicity

Screening Outcome Negative
Screening Method
Data Results in vitro Mutagenicity
Reference LBI, 1976, unpublished data (as cited in BIBRA, 1988) Zeiger, 1988, Environ Mol Mutagen, 19(Suppl. 21):2-141 FDA,1976, unpublished data Heck, 1989, Toxicologist, 9(1):257 (all cited in JECFA, 1998)

Developmental Toxicity

Screening Outcome Negative
Screening Method
Data Results LO(A)EL 1500 mg/kg bw
Reference Narotsky, 1994, Fundam Appl Toxicol, 22:251-265. (as cited in JECFA, 1998) Collins (abstract only), 1986, Teratology, 33:45C, Abstract 50 (as cited in BIBRA, 1988) Nau, 1986, Fund Appl Toxic 6:669 (as cited in BIBRA, 1988)