Substance Identity
CAS Number 95-55-6
Chemical Name Phenol, 2-amino-
Type of substance Organic
SMILES Oc(c(N)ccc1)c1
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT QSAR
DSL Quantity range (tonnes/year) >1T to 1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 95
Reference (biodegradation result) PITTER,P.; DETERMINATION OF BIOLOGICAL DEGRADABILITY OF ORGANIC SUBSTANCES.; WATER RES.; 10:231-5.; 1976
Robust Study Summary (biodegradation result)
95556.doc
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.2927
TOPKAT probability of biodegradation 0.633
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 0.1441

Underlying data regarding Bioaccumulation

Empirical Log Kow 0.62
Log Kow predicted by KowWin 0.6
Log BAF T2MTL predicted by Gobas 0.0792401263405732
Log BCF 5% T2LTL predicted by Gobas 0.0650536719899916
Log BCF Max predicted by OASIS 1.15868933054699
Log BCF predicted by BCFWIN 0.5

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 92.9
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 92.9
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 116.772
Toxicity to fish (LC50 in mg/l) as predicted by Aster 221.939656
Toxicity to fish (LC50 in mg/l) as predicted by PNN 31.94227
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 0.5413
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 291.836
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 5.58E+002

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
EC Genotoxicity - Category 3

Underlying data regarding Complex Hazard Assessment