Substance Identity
CAS Number 109-69-3
Chemical Name Butane, 1-chloro-
Type of substance Organic
SMILES ClCCCC
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B Experiment
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) >1T to 1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Air
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.6276
TOPKAT probability of biodegradation 0.665
EPI Predicted hydrolysis half-life (days) 2.82E+014
EPI Predicted Ozone reaction half-life (days) 999
Experimental Atmospheric Oxidation half-life (days) 7.12962962962963
Reference (oxidation) ATKINSON,R.; KINETICS AND MECHANISMS OF THE GAS-PHASE REACTIONS OF THE HYDROXYL RADICAL WITH ORGANIC COMPOUNDS.; JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA. MONOGRAPH NO. 1.; 1989
EPI Predicted Atmospheric Oxidation half-life (days) 4.938

Underlying data regarding Bioaccumulation

Empirical Log Kow 2.64
Reference (Log Kow) HANSCH,C & LEO,AJ (1985)
Log Kow predicted by KowWin 2.56
Log BAF T2MTL predicted by Gobas 0.92166693940192
Log BCF 5% T2LTL predicted by Gobas 0.896365528120849
Log BCF Max predicted by OASIS 2.05316393125448
Log BCF predicted by BCFWIN 1.333
Experimental BCF (log) 1.14939966233098
Reason for pivotal value Average Vertebrate BCF
Test species BCF/BAF (Latin) Cyprinus carpio
Test species BCF/BAF (Common) Common carp
Mean water concentration (ug/l) 50
Mean water concentration (comment) Below water solubility by a factor of 5
Water concentration: Measured/Nominal/Uncertain Measured
RadioLabel No
Exposure duration (days) 42
Exposure duration (comment) Sufficient exposure duration for 80% steady state; "Reported steady state"
Exposure type Flow-through
Mean temperature (deg. Celcius) 22
Exposure route Water (but fed)
Exposure media Fresh Water
Mean measured lipid content (%) 3.7
Tissue analysed Whole body
Calculation method Cb/Cw
Comment (BAF/BCF) Average BCF; Apparent measured water concentrations; Reported "Steady state"
Reference (BAF/BCF) Chemicals Evaluation and Research Institute. 1992. Biodegradation and Bioconcentration of Existing Chemical Substances under the Chemical Substances Control Law. http://qsar.cerij.or.jp/cgi-bin/DEGACC/index.cgi?e

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 3020
Experimental result iT (mg/l) 3020
Test species iT (Latin) Daphnia mag
Test species iT (Common) Water flea
Final EndPoint iT EC50
Exposure duration iT (hours) 48
Reference iT Water Res. 23(4):495-499 (OECDG Data File)
Robust Study Summary iT
109693-AT-EC50-I-Dapmag.doc
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 40.6
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 20.421
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 63.8474
Toxicity to fish (LC50 in mg/l) as predicted by Aster 22.594137
Toxicity to fish (LC50 in mg/l) as predicted by PNN 15.24254
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 223.3
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 3.949
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 1.49
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 2.04E+001

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment