Substance Identity
CAS Number 126-07-8
Chemical Name Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'.beta.-methyl-
Type of substance Organic
SMILES COc1c(Cl)c2OC(C(OC)=C3)(C(C)CC3=O)C(=O)c2c(OC)c1
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P QSAR
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? Yes
Rational for iT QSAR
DSL Quantity range (tonnes/year) Unknown Quantity

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water-Soil
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 60
MITI probability of biodegradation 0.1656
EPI Predicted Ozone reaction half-life (days) 1.31
EPI Predicted Atmospheric Oxidation half-life (days) 0.03196

Underlying data regarding Bioaccumulation

Empirical Log Kow 2.18
Log Kow predicted by KowWin 1.92
Log BAF T2MTL predicted by Gobas 1.02197597222153
Log BCF 5% T2LTL predicted by Gobas 0.937867243577101
Log BCF Max predicted by OASIS 1.64847458499385
Log BCF predicted by BCFWIN 0.139

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 0.0164
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 0.0164
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 259.882
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 395.0812
Toxicity to fish (LC50 in mg/l) as predicted by PNN 0.03522
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 556.131
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 3.11E+000

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
IARC Carcinogenicity - Group 2B

Underlying data regarding Complex Hazard Assessment