Substance Identity
CAS Number 59-50-7
Chemical Name Phenol, 4-chloro-3-methyl-
Type of substance Organic
SMILES Oc(ccc(c1C)Cl)c1
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? Yes
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? Yes
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B Experiment
Inherently Toxic to Aquatic Organisms (iT)? Yes
Rational for iT Experiment
DSL Quantity range (tonnes/year) 0 to 1T
Basis for Environment Categorization (PiT, BiT, PBiT) if categorized? PiT

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water-Soil
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 0
Reference (biodegradation result) CHEMICALS INSPECTION AND TESTING INSTITUTE.; BIODEGRADATION AND BIOACCUMULATION DATA OF EXISTING CHEMICALS BASED ON THE CSCL JAPAN.; JAPAN CHEMICAL INDUSTRY ECOLOGY - TOXICOLOGY AND INFORMATION CENTER.ISBN 4-89074-101-1.; 1992
Robust Study Summary (biodegradation result)
59507.doc
MITI book - P data.doc
Predicted Ultimate degradation half-life (days) 37.5
MITI probability of biodegradation 0.3422
TOPKAT probability of biodegradation 0.002
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 0.4165

Underlying data regarding Bioaccumulation

Empirical Log Kow 3.1
Reference (Log Kow) HANSCH,C & LEO,AJ (1985)
Log Kow predicted by KowWin 2.7
Log BAF T2MTL predicted by Gobas 0.53938881105455
Log BCF 5% T2LTL predicted by Gobas 0.538415726916026
Log BCF Max predicted by OASIS 2.16122361227058
Log BCF predicted by BCFWIN 1.687
Experimental BCF (log) 0.953794939615272
Reason for pivotal value Average Vertebrate BCF
Test species BCF/BAF (Latin) Cyprinus carpio
Test species BCF/BAF (Common) Common carp
Mean water concentration (ug/l) 2
Mean water concentration (comment) Below water solubility by a factor of 5
Water concentration: Measured/Nominal/Uncertain Measured
RadioLabel No
Exposure duration (days) 42
Exposure duration (comment) Sufficient exposure duration for 80% steady state; "Reported steady state"
Exposure type Flow-through
Mean temperature (deg. Celcius) 22
Exposure route Water (but fed)
Exposure media Fresh Water
Mean measured lipid content (%) 4.9
Tissue analysed Whole body
Calculation method Cb/Cw
Comment (BAF/BCF) Average BCF; Apparent measured water concentrations; Reported "Steady state"
Reference (BAF/BCF) Chemicals Evaluation and Research Institute. 1992. Biodegradation and Bioconcentration of Existing Chemical Substances under the Chemical Substances Control Law. http://qsar.cerij.or.jp/cgi-bin/DEGACC/index.cgi?e

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 0.917
Experimental result iT (mg/l) 0.917
Test species iT (Latin) Oncorhynchus mykiss
Test species iT (Common) Rainbow trout,doldson trout
Final EndPoint iT LC50
Exposure duration iT (hours) 96
Reference iT Environmental Fate and Effects Division, U.S.EPA, Washington, D.C.
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 8.6
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 7.76
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 14.4106
Toxicity to fish (LC50 in mg/l) as predicted by Aster 8.406282
Toxicity to fish (LC50 in mg/l) as predicted by PNN 7.12051
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 1.4
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 17.005
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 7.74E+000

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment