Substance Identity
CAS Number 75-09-2
Chemical Name Methane, dichloro-
Type of substance Organic
SMILES ClCCl
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B Experiment
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) >1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Air
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 5
Reference (biodegradation result) CHEMICALS INSPECTION AND TESTING INSTITUTE.; BIODEGRADATION AND BIOACCUMULATION DATA OF EXISTING CHEMICALS BASED ON THE CSCL JAPAN.; JAPAN CHEMICAL INDUSTRY ECOLOGY - TOXICOLOGY AND INFORMATION CENTER.ISBN 4-89074-101-1.; 1992
Robust Study Summary (biodegradation result)
MITI book - P data.doc
Predicted Ultimate degradation half-life (days) 37.5
MITI probability of biodegradation 0.3154
TOPKAT probability of biodegradation 0
EPI Predicted hydrolysis half-life (days) 1.57E+010
EPI Predicted Ozone reaction half-life (days) 999
Experimental Atmospheric Oxidation half-life (days) 75.3129890453834
Reference (oxidation) ATKINSON,R.; KINETICS AND MECHANISMS OF THE GAS-PHASE REACTIONS OF THE HYDROXYL RADICAL WITH ORGANIC COMPOUNDS.; JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA. MONOGRAPH NO. 1.; 1989
EPI Predicted Atmospheric Oxidation half-life (days) 79.31

Underlying data regarding Bioaccumulation

Empirical Log Kow 1.25
Reference (Log Kow) HANSCH,C & LEO,AJ (1985)
Log Kow predicted by KowWin 1.34
Log BAF T2MTL predicted by Gobas 0.313844785168765
Log BCF 5% T2LTL predicted by Gobas 0.268546632165463
Log BCF Max predicted by OASIS 1.38092559798228
Log BCF predicted by BCFWIN 0.262
Experimental BCF (log) 0.965210375349291
Reason for pivotal value Average Vertebrate BCF
Test species BCF/BAF (Latin) Cyprinus carpio
Test species BCF/BAF (Common) Common carp
Mean water concentration (ug/l) 250
Mean water concentration (comment) Below water solubility by a factor of 5
Water concentration: Measured/Nominal/Uncertain Measured
RadioLabel No
Exposure duration (days) 42
Exposure duration (comment) Sufficient exposure duration for 80% steady state; "Reported steady state"
Exposure type Flow-through
Mean temperature (deg. Celcius) 22
Exposure route Water (but fed)
Exposure media Fresh Water
Mean measured lipid content (%) 4.6
Tissue analysed Whole body
Calculation method Cb/Cw
Comment (BAF/BCF) Average BCF; Apparent measured water concentrations; Reported "Steady state"
Reference (BAF/BCF) Chemicals Evaluation and Research Institute. 1992. Biodegradation and Bioconcentration of Existing Chemical Substances under the Chemical Substances Control Law. http://qsar.cerij.or.jp/cgi-bin/DEGACC/index.cgi?e

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 32
Experimental result iT (mg/l) 32
Exposure duration iT (hours) 96
Robust Study Summary iT
75092-AT-LC50-F-pimpro.doc
75092-AT-LC50-O-rancat.doc
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 262.71
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 758.1719
Toxicity to fish (LC50 in mg/l) as predicted by Aster 320.263938
Toxicity to fish (LC50 in mg/l) as predicted by PNN 27.66078
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 59.5
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 121.36
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 10.334
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 2.63E+002

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Greatest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Previous assessment through previous CEPA assessment

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
HC Carcinogenicity - Group II
EC Carcinogenicity - Category 3
IARC Carcinogenicity - Group 2B
USEPA 1986 Carcinogenicity - Groups B1 and B2
NTP Carcinogenicity - Reasonably anticipated to be a human carcinogen

Underlying data regarding Complex Hazard Assessment