Substance Identity
CAS Number 110-86-1
Chemical Name Pyridine
Type of substance Organic
SMILES n(cccc1)c1
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? No
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) >1T to 1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 91
Reference (biodegradation result) GERIKE,P.; FISCHER,W.K.; A CORRELATION STUDY OF BIODEGRADABILITY DETERMINATIONS WITH VARIOUS CHEMICALS IN VARIOUS TESTS. II. ADDITIONAL RESULTS AND CONCLUSIONS.; ECOTOXICOL. ENVIRON. SAFETY.; 5:45-55.; 1981
Robust Study Summary (biodegradation result)
110861.doc
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.5946
TOPKAT probability of biodegradation 0.997
EPI Predicted Ozone reaction half-life (days) 999
Experimental Atmospheric Oxidation half-life (days) 28.9039039039039
Reference (oxidation) ATKINSON,R.; KINETICS AND MECHANISMS OF THE GAS-PHASE REACTIONS OF THE HYDROXYL RADICAL WITH ORGANIC COMPOUNDS.; JOURNAL OF PHYSICAL AND CHEMICAL REFERENCE DATA. MONOGRAPH NO. 1.; 1989
EPI Predicted Atmospheric Oxidation half-life (days) 28.91

Underlying data regarding Bioaccumulation

Empirical Log Kow 0.65
Log Kow predicted by KowWin 0.8
Log BAF T2MTL predicted by Gobas 0.0859985546026171
Log BCF 5% T2LTL predicted by Gobas 0.0707013887661259
Log BCF Max predicted by OASIS 1.20917730603076
Log BCF predicted by BCFWIN 0.5

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 26
Experimental result iT (mg/l) 26
Test species iT (Latin) Cyprinus carpio
Test species iT (Common) Common, mirror, colored, carp
Final EndPoint iT LC50
Exposure duration iT (hours) 96
Reference iT Indian J.Environ.Health 17(2):140-146
Robust Study Summary iT
110861-AT-LC50-F-cypcar.rtf
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 787.388
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 2,195.6953
Toxicity to fish (LC50 in mg/l) as predicted by Aster 154.502031
Toxicity to fish (LC50 in mg/l) as predicted by PNN 192.43691
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 10.4
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 453.094
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 23.561
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 2.62E+002

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Intermediate Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment