Substance Identity
CAS Number 12002-48-1
Chemical Name Benzene, trichloro-
Type of substance Organic
SMILES Clc1cc(cc(c1)Cl)Cl
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B Experiment
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) >1T to 1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Air-Soil
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 0
Reference (biodegradation result) CHEMICALS INSPECTION AND TESTING INSTITUTE.; BIODEGRADATION AND BIOACCUMULATION DATA OF EXISTING CHEMICALS BASED ON THE CSCL JAPAN.; JAPAN CHEMICAL INDUSTRY ECOLOGY - TOXICOLOGY AND INFORMATION CENTER.ISBN 4-89074-101-1.; 1992
Robust Study Summary (biodegradation result)
MITI book - P data.doc
Predicted Ultimate degradation half-life (days) 60
MITI probability of biodegradation 0.047
TOPKAT probability of biodegradation 0.096
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 15.76

Underlying data regarding Bioaccumulation

Empirical Log Kow 4.19
Reference (Log Kow) EPISUITE KOWWIN v1.67
Log Kow predicted by KowWin 3.93
Log BAF T2MTL predicted by Gobas 3.10197149033974
Log BCF 5% T2LTL predicted by Gobas 2.89343883190288
Log BCF Max predicted by OASIS 3.25357472149441
Log BCF predicted by BCFWIN 2.526
Experimental BCF (log) 3.06
Reason for pivotal value Highest Vertebrate BCF
Test species BCF/BAF (Latin) Poecilia reticulata
Test species BCF/BAF (Common) Guppy
Mean water concentration (ug/l) 136
Mean water concentration (comment) Below water solubility by a factor of 5
Water concentration: Measured/Nominal/Uncertain Measured
RadioLabel No
Exposure duration (days) 16.9
Exposure duration (comment) Sufficient exposure duration for 80% steady state; K1/K2
Exposure type Flow-through
Mean temperature (deg. Celcius) 21
Exposure route Water
Exposure media Fresh Water
Tissue analysed Whole body
Calculation method Cb/Cw
Reference (BAF/BCF) Van Eck, J.M.C., A.A. Koelmans, and J.W. Deneer. 1997. Uptake and Elimination of 1,2,4-Trichlorobenzene in the Guppy (Poecilia reticulata) at Sublethal and Lethal Aqueous Concentrations. Chemosphere 34(11):2259-2270

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 100
Experimental result iT (mg/l) 100
Test species iT (Latin) Daphnia mag
Test species iT (Common) Water flea
Final EndPoint iT LC50
Exposure duration iT (hours) 24
Reference iT Z.Wasser-Abwasser-Forsch.10(5):161-166 (GER) (ENG ABS); TR-79-1204, Literature Research Company :13 p. (ENG TRANSL) (OECDG Data File)
Robust Study Summary iT
12002481-AT-EC50-I-Mermer.doc
12002481-AT-EC50-I-Cravir.doc
12002481_AT_LC50_dapmag-3.doc
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 7,800
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 2.063
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 2.1229
Toxicity to fish (LC50 in mg/l) as predicted by Aster 2.11061
Toxicity to fish (LC50 in mg/l) as predicted by PNN 1.96534
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 2.9
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 0.15
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 0.301
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 2.06E+000

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment