Substance Identity
CAS Number 108-43-0
Chemical Name Phenol, 3-chloro-
Type of substance Organic
SMILES Oc(cccc1Cl)c1
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? No
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B Experiment
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) 0 to 1T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Air-Water-Soil
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 0
Reference (biodegradation result) CHEMICALS INSPECTION AND TESTING INSTITUTE.; BIODEGRADATION AND BIOACCUMULATION DATA OF EXISTING CHEMICALS BASED ON THE CSCL JAPAN.; JAPAN CHEMICAL INDUSTRY ECOLOGY - TOXICOLOGY AND INFORMATION CENTER.ISBN 4-89074-101-1.; 1992
Robust Study Summary (biodegradation result)
MITI book - P data.doc
Predicted Ultimate degradation half-life (days) 15
MITI probability of biodegradation 0.3927
TOPKAT probability of biodegradation 0.088
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 0.4535

Underlying data regarding Bioaccumulation

Empirical Log Kow 2.5
Reference (Log Kow) HANSCH,C & LEO,AJ (1985)
Log Kow predicted by KowWin 2.16
Log BAF T2MTL predicted by Gobas 0.757526271899246
Log BCF 5% T2LTL predicted by Gobas 0.736673134449052
Log BCF Max predicted by OASIS 1.78415863669762
Log BCF predicted by BCFWIN 1.225
Experimental BCF (log) 1.25
Reason for pivotal value Highest Vertebrate BCF
Test species BCF/BAF (Latin) Brachydanio rerio
Test species BCF/BAF (Common) Zebrafish
Mean water concentration (ug/l) 980
Mean water concentration (comment) Below water solubility by a factor of 5
Water concentration: Measured/Nominal/Uncertain Measured
RadioLabel No
Exposure duration (comment) Uncertain exposure duration; K1/K2
Exposure type Flow-through
Mean temperature (deg. Celcius) 25
Exposure route Water
Exposure media Fresh Water
Mean measured lipid content (%) 4
Tissue analysed Whole body
Calculation method K1/K2
Reference (BAF/BCF) Butte, W., Willing, A., Zauke, G.-P.. 1987. Bioaccumulation of Phenols in Zebrafish Determined by a Dynamic Flow Through Test. QSAR in Environmental Toxicology II pp.43-53 (K.L.E. Kaiser, Ed)

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 3.99
Experimental result iT (mg/l) 3.99
Test species iT (Latin) Platichthys flesus
Test species iT (Common) Starry, european flounder
Final EndPoint iT LC50
Exposure duration iT (hours) 96
Reference iT Chemosphere 28(4):825-836
Robust Study Summary iT
108430-AT-LC50-I-Gup.doc
108430-AT-LC50-F-Plafle-2.doc
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 16.5
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 15.05
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 35.2922
Toxicity to fish (LC50 in mg/l) as predicted by Aster 15.994826
Toxicity to fish (LC50 in mg/l) as predicted by PNN 4.1547
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 1.2
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 46.079
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 2.25E+001

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment