Substance Identity
CAS Number 95-51-2
Chemical Name Benzenamine, 2-chloro-
Type of substance Organic
SMILES Nc(c(ccc1)Cl)c1
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? Yes
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? Yes
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B Experiment
Inherently Toxic to Aquatic Organisms (iT)? Yes
Rational for iT Experiment
DSL Quantity range (tonnes/year) 0 to 1T
Basis for Environment Categorization (PiT, BiT, PBiT) if categorized? PiT

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 2.7
Reference (biodegradation result) CHEMICALS INSPECTION AND TESTING INSTITUTE.; BIODEGRADATION AND BIOACCUMULATION DATA OF EXISTING CHEMICALS BASED ON THE CSCL JAPAN.; JAPAN CHEMICAL INDUSTRY ECOLOGY - TOXICOLOGY AND INFORMATION CENTER.ISBN 4-89074-101-1.; 1992
Robust Study Summary (biodegradation result)
MITI book - P data.doc
Predicted Ultimate degradation half-life (days) 37.5
MITI probability of biodegradation 0.107
TOPKAT probability of biodegradation 0.005
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 0.3403

Underlying data regarding Bioaccumulation

Empirical Log Kow 1.9
Reference (Log Kow) HANSCH,C & LEO,AJ (1985)
Log Kow predicted by KowWin 1.72
Log BAF T2MTL predicted by Gobas 0.488191909619032
Log BCF 5% T2LTL predicted by Gobas 0.458824574225647
Log BCF Max predicted by OASIS 1.54544176969394
Log BCF predicted by BCFWIN 0.763
Experimental BCF (log) 0.772516152963694
Reason for pivotal value Average Vertebrate BCF
Test species BCF/BAF (Latin) Cyprinus carpio
Test species BCF/BAF (Common) Common carp
Mean water concentration (ug/l) 16.1
Mean water concentration (comment) Below water solubility by a factor of 5
Water concentration: Measured/Nominal/Uncertain Measured
RadioLabel No
Exposure duration (days) 14
Exposure duration (comment) Sufficient exposure duration for 80% steady state
Exposure type Flow-through
Mean temperature (deg. Celcius) 25
Exposure route Water (but fed)
Exposure media Fresh Water
Tissue analysed Uncertain
Calculation method Cb/Cw
Reference (BAF/BCF) Tsuda, T., S. Aoki, M. Kojima and T. Fujita. 1993. Accumulation and Excretion of Chloroanilines by Carp. Chemosphere 26:2301-2306

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 0.45
Experimental result iT (mg/l) 0.45
Test species iT (Latin) Daphnia mag
Test species iT (Common) Water flea
Final EndPoint iT EC50
Exposure duration iT (hours) 48
Reference iT Proj.No.303587, Report to the Danish EPA, Copenhagen, Denmark :93 p.
Robust Study Summary iT
95512-AT-EC50-I-dapmag-21.doc
95512-AT-LC50-I-dapmag.doc
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 19.1
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 61.757
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 76.7976
Toxicity to fish (LC50 in mg/l) as predicted by Aster 37.632227
Toxicity to fish (LC50 in mg/l) as predicted by PNN 9.5493
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 1.1
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 26.693
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 5.78E+001

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment