Substance Identity
CAS Number 10540-29-1
Chemical Name Ethanamine, 2-[4-[(1Z)-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethyl-
Type of substance Organic
SMILES c1ccccc1C(CC)=C(c2ccccc2)c3ccc(OCCN(C)C)cc3
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? Yes
Meets Human Health Categorization Criteria? Yes
Meets Environmental Criteria for Categorization? Yes
Persistent (P)? No
Rational for P QSAR
Bioaccumulative (B)? Yes
Rational for B QSAR
Inherently Toxic to Aquatic Organisms (iT)? Yes
Rational for iT Experiment
DSL Quantity range (tonnes/year) Unknown Quantity
Basis for Environment Categorization (PiT, BiT, PBiT) if categorized? BiT

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Soil
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 60
MITI probability of biodegradation 0.0091
EPI Predicted Ozone reaction half-life (days) 0.000583
EPI Predicted Atmospheric Oxidation half-life (days) 0.0444

Underlying data regarding Bioaccumulation

Log Kow predicted by KowWin 6.3
Log BAF T2MTL predicted by Gobas 6.03146037587664
Log BCF 5% T2LTL predicted by Gobas 4.57455402075921
Log BCF Max predicted by OASIS 4.82721449593747
Log BCF predicted by BCFWIN 4.153

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 0.049
Experimental result iT (mg/l) 0.049
Test species iT (Latin) Acartia tonsa
Test species iT (Common) Calanoid copepod
Final EndPoint iT EC50
Exposure duration iT (hours) 120
Reference iT Environ.Toxicol.Chem. 20(12):2821-2829
Robust Study Summary iT
10540291-CT-EC50-I-acaton.doc
Toxicity to fathead minnow (LC50 in mg/l) as predicted by Topkat v6.1 0.0011
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 0.181
Toxicity to fish (LC50 in mg/l) as predicted by PNN 0.76091
Toxicity to daphnia (EC50 in mg/l) as predicted by Topkat v6.1 1.8
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 0.09
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 8.97E-004

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
NTP Carcinogenicity - Known to be a human carcinogen
IARC Carcinogenicity - Group 1

Underlying data regarding Complex Hazard Assessment