Substance Identity
CAS Number 108-78-1
Chemical Name 1,3,5-Triazine-2,4,6-triamine
Type of substance Organic
SMILES n(c(nc(n1)N)N)c1N
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? Yes
Meets Human Health Categorization Criteria? Yes
Meets Environmental Criteria for Categorization? No
Persistent (P)? Yes
Rational for P Experiment
Bioaccumulative (B)? No
Rational for B Experiment
Inherently Toxic to Aquatic Organisms (iT)? No
Rational for iT Experiment
DSL Quantity range (tonnes/year) >1000T

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Water
Experimental Biodegradation half-life (days) Not Available
Experimental Biodegradation result (%) 0
Reference (biodegradation result) CHEMICALS INSPECTION AND TESTING INSTITUTE.; BIODEGRADATION AND BIOACCUMULATION DATA OF EXISTING CHEMICALS BASED ON THE CSCL JAPAN.; JAPAN CHEMICAL INDUSTRY ECOLOGY - TOXICOLOGY AND INFORMATION CENTER.ISBN 4-89074-101-1.; 1992
Robust Study Summary (biodegradation result)
108781.doc
MITI book - P data.doc
Predicted Ultimate degradation half-life (days) 37.5
MITI probability of biodegradation 0
TOPKAT probability of biodegradation 0.038
EPI Predicted Ozone reaction half-life (days) 999
EPI Predicted Atmospheric Oxidation half-life (days) 16.22

Underlying data regarding Bioaccumulation

Empirical Log Kow -1.37
Reference (Log Kow) CLOGP (1986)
Log Kow predicted by KowWin -0.38
Log BAF T2MTL predicted by Gobas -0.0270545659449223
Log BCF 5% T2LTL predicted by Gobas -0.021326208939628
Log BCF Max predicted by OASIS 1.0118328404815
Log BCF predicted by BCFWIN 0.5
Experimental BCF (log) 0.0799999999999995
Reason for pivotal value Average Vertebrate BCF
Test species BCF/BAF (Latin) Cyprinus carpio
Test species BCF/BAF (Common) Common carp
Mean water concentration (ug/l) 2,000
Mean water concentration (comment) Below water solubility by a factor of 5
Water concentration: Measured/Nominal/Uncertain Measured
RadioLabel No
Exposure duration (days) 42
Exposure duration (comment) Sufficient exposure duration for 80% steady state; "Reported steady state"
Exposure type Flow-through
Mean temperature (deg. Celcius) 22
Exposure route Water (but fed)
Exposure media Fresh Water
Tissue analysed Whole body
Calculation method Cb/Cw
Comment (BAF/BCF) Average BCF; Apparent measured water concentrations; Reported "Steady state"
Reference (BAF/BCF) Chemicals Evaluation and Research Institute. 1992. Biodegradation and Bioconcentration of Existing Chemical Substances under the Chemical Substances Control Law. http://qsar.cerij.or.jp/cgi-bin/DEGACC/index.cgi?e

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 1000
Experimental result iT (mg/l) 1000
Test species iT (Latin) Oryzias latipes
Test species iT (Common) orange-red killifish
Final EndPoint iT LC50
Reference iT CHEMICALS INSPECTION AND TESTING INSTITUTE.; BIODEGRADATION AND BIOACCUMULATION DATA OF EXISTING CHEMICALS BASED ON THE CSCL JAPAN.; JAPAN CHEMICAL INDUSTRY ECOLOGY - TOXICOLOGY AND INFORMATION CENTER.ISBN 4-89074-101-1.; 1992
Robust Study Summary iT
RSS - MITI book.doc
Toxicity to fish (LC50 in mg/l) as predicted by Ecosar v0.99g 16,143.181
Toxicity to fish (LC50 in mg/l) as predicted by Oasis Forecast M v1.10 77,204.4844
Toxicity to fish (LC50 in mg/l) as predicted by PNN 795.48816
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 14,675.373
Chronic toxicity to daphnia or algae (EC50 in mg/l) as predicted by Ecosar v0.99g 265.699
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 1.61E+002

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Greatest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Underlying data regarding Simple Hazard Assessment


Underlying data regarding Complex Hazard Assessment