Substance Identity
CAS Number 12789-03-6
Chemical Name Chlordane
Type of substance Organic
SMILES ClC(C(Cl)C1)C(C1C2(Cl)C=3Cl)C(Cl)(C3Cl)C2(Cl)Cl
Moiety of concern organic
Categorization Results

Meets Government of Canada Categorization Criteria? Yes
Meets Human Health Categorization Criteria? No
Meets Environmental Criteria for Categorization? Yes
Persistent (P)? Yes
Rational for P QSAR
Bioaccumulative (B)? Yes
Rational for B Experiment
Inherently Toxic to Aquatic Organisms (iT)? Yes
Rational for iT Experiment
DSL Quantity range (tonnes/year) Unknown Quantity
Basis for Environment Categorization (PiT, BiT, PBiT) if categorized? PBiT

Ecological data supporting decisions

Underlying data regarding persistence

Media of concern leading to Categorization Soil
Experimental Biodegradation half-life (days) Not Available
Predicted Ultimate degradation half-life (days) 182
MITI probability of biodegradation 0
EPI Predicted Ozone reaction half-life (days) 320.2
EPI Predicted Atmospheric Oxidation half-life (days) 2.123

Underlying data regarding Bioaccumulation

Empirical Log Kow 6.22
Reference (Log Kow) EPISUITE KOWWIN v1.67
Log Kow predicted by KowWin 6.26
Log BAF T2MTL predicted by Gobas 5.95101151033439
Log BCF 5% T2LTL predicted by Gobas 4.55139952089638
Log BCF Max predicted by OASIS 4.82362320058018
Log BCF predicted by BCFWIN 4.09
Experimental BAF (log) 5.95
Experimental BCF (log) 4.19554390040747
Reason for pivotal value Highest Vertebrate BAF
Test species BCF/BAF (Latin) Cottus cognatus
Test species BCF/BAF (Common) Sculpin
Mean water concentration (ug/l) 0.000034
Mean water concentration (comment) Below water solubility by a factor of 5
Water concentration: Measured/Nominal/Uncertain Measured
RadioLabel No
Exposure duration (comment) Lifetime exposure; assumed steady state
Exposure type Lentic
Mean temperature (deg. Celcius) 8
Exposure route Water & Diet
Exposure media Fresh Water
Mean measured lipid content (%) 8
Tissue analysed Whole body
Calculation method Cb/Cw
Comment (BAF/BCF) Average BAF - Lake Ontario
Reference (BAF/BCF) Oliver, B.G. and A.J. Niimi. 1988. Trophodynamic Analysis of Polychlorinated Biphenyl Congeners and Other Chlorinated Hydrocarbons in the Lake Ontario Ecosystem.. Environ. Sci Technol. 22:388-397

Underlying data regarding inherent toxicity to aquatic organisms

Pivotal value for iT (mg/l) 0.0004
Experimental result iT (mg/l) 0.0004
Test species iT (Latin) Penaeus duorarum
Test species iT (Common) Northern pink shrimp
Final EndPoint iT LC50
Exposure duration iT (hours) 96
Reference iT Parrish, P.R., Schimmel, S.C., Hansen, D.J., Patrick, Jr, J. M. and J. Forester. 1976. Chordane: Effects on several estuarine organisms. Journal of T oxicology and Environmental Health. 1: 485-494.
Robust Study Summary iT
12789036-AT-96hLC50EC50-invertsfish.doc
Toxicity to fish (LC50 in mg/l) as predicted by PNN 0.01451
Toxicity to fish, daphnia, algae or mysid shrimp (EC50 or LC50 in mg/l) as predicted by Ecosar v0.99g 0.107
Toxicity to fish (LC50 in mg/l) as predicted by Neutral Organics QSAR in Ecosar v0.99g 1.07E-003

Human Health data supporting decisions
Underlying data regarding potential for exposure

LPE/IPE/GPE Lowest Potential for Exposure (HC Simple Exposure Tool)

Underlying data regarding Previous Assessments

Previous assessment through SimHaz Priority

Underlying data regarding Simple Hazard Assessment

AgencyAssessment
USEPA 1986 Carcinogenicity - Groups B1 and B2

Underlying data regarding Complex Hazard Assessment